Overview

NOCIt software is designed to provide accurate probabilities on the number of contributors (NoC) in DNA mixtures, which is a critical element of forensic DNA mixture interpretation. Developed to support forensic biology and forensic DNA typing, NOCIt is compatible with output from genotyping software such as GeneMarkerHID and GeneMapperIDX, and provides essential information for probabilistic genotyping (PG) analysis in software like MaSTR, STRMix, or EuroForMix. This software utilizes peak heights, stutter, and drop-out data to deliver precise results, making it consistent with PG models when analyzing mixtures with assumed contributors, such as victims. NOCIt software is validated and offers a posteriori probability (APP) distribution on the number of contributors for STR data. It provides accurate results with unimodal distributions and allows easy and rapid calibration to laboratory-specific data. The software supports conditioning to known or assumed contributors, enhancing its utility in complex forensic cases.

Features

• Compatibility: Works with output from genotyping software like GeneMarkerHID and GeneMapperIDX.
• Probabilistic Analysis: Provides APP distribution on the number of contributors for STR data.
• Accuracy: Delivers accurate results with unimodal distributions.
• Calibration: Allows easy and rapid calibration to laboratory-specific data.
• Data Utilization: Utilizes peak heights, stutter, and drop-out data for precise analysis.
• Conditioning: Supports conditioning to known or assumed contributors.
• Integration: Provides essential information for PG analysis in software like MaSTR, STRMix, or EuroForMix.