Overview

Mutation Surveyor by SoftGenetics is a robust DNA variant analysis software designed for Sanger sequencing files. It includes patented anti-correlation technology that physically compares sample sequence traces to a reference trace, providing exceptional accuracy and sensitivity. Mutation Surveyor is capable of performing variant analysis on up to 2000 Sanger sequencing files in just 15 minutes, making it an essential tool for genetic research and diagnostics.

Features

• Anti-Correlation Technology: The patented anti-correlation technology compares sample sequence traces to a reference trace, achieving up to 99.5% accuracy with Phred 20 bi-directional sequences and a sensitivity of 5% of the primary peak.
• Variant Analysis: Perform variant analysis of DNA variants, including single nucleotide polymorphisms (SNPs), homozygous insertions and deletions (indels), heterozygous indels, and somatic mutations.
• Custom Reporting: Generate custom reports with automated download of annotated GenBank reference files, DNA methylation detection, mitochondrial DNA sequence analysis, allele quantification, and variant knowledge database.
• Trace Alignment: Automatically align traces to GRCh37 or GRCh38 GenBank references, ensuring accurate variant discovery.
• User Management: Utilize an intuitive user management system to set up password-protected user names, control access rights, and generate a user audit trail.
• Sensitivity: Detect low-frequency alleles associated with somatic mutations, heteroplasmy, and mosaicism with enhanced sensitivity.
• Mutation Quantification: Quantify major and minor allele contributions with the Mutation Quantification tool, providing detailed analysis of variant peaks.
• Application Notes: Access application notes for DNA mutation and methylation quantification, heterozygous DNA INDEL analysis, and sequence assembly.