ACD/AutoChrom assists chromatography experts in developing chromatographic separations by applying Quality by Design (QbD) principles. The software employs a workflow-based structure to streamline and track projects, enabling users to begin with reasonable starting conditions and columns, define a strategy with software wizards, and automatically run experiments for screening and optimization. It models separations in 1D, 2D, or 3D, and documents decisions for data integrity and future learning. AutoChrom helps reduce unnecessary experiments by simulating chromatograms to see how the separation will look under new conditions. The dashboard provides a view of the project, including the workflow strategy, experimental steps, and instrument configuration. The software also assists in finding the best pH by predicting logD for each pH, and features a peak-matching algorithm to simplify the tracking of UV and MS peaks. The Column Selector aids in picking the right columns with the help of radar graphs.

Features & Benefits

Take a strategic approach

• Start your project by predicting compound properties and building a development strategy
• Work through the steps logically and move closer to optimization with every experiment Manage your project from start to documentation
• Document your decisions for data integrity
• Store the workflow alongside the experimental data and solutions
• Upload everything to a searchable database so your team can find it again Automate screening and optimization trials
• Walk away, and AutoChrom Online will run your experiments automatically according to your strategy Find optimal conditions by simulation
• Optimize your separation in 1D, 2D, or 3D with color-coded resolution and suitability maps Algorithmically track peaks between runs
• Track a compound across multiple chromatograms by UV or MS spectra, with help from AutoChrom’s algorithms Reduce unnecessary experiments
• Cut down on experiments and development time with simulation and computer-assisted modeling