The ONI neuroscience platform utilizes the Nanoimager, a compact super-resolution microscope, to provide high-resolution imaging of cultured neuronal cells and brain tissue sections. This platform supports both fixed and live sample imaging, allowing researchers to develop custom assays for comprehensive spatio-temporal analysis of neuronal pathways. The system's single-molecule sensitivity facilitates improved diagnostics and therapeutic development by enabling detailed characterization of synaptic architecture and protein dynamics in healthy and diseased tissues.

Key Features

Super-Resolution Imaging Enables imaging with a resolution reaching 20 nanometers.

• Supports both fixed and live sample imaging.
• Facilitates detailed analysis of synaptic architecture and protein distribution.

Single-Molecule Sensitivity Allows for the detection and tracking of individual molecules.

• Enables the study of protein dynamics in living brains.
• Supports simultaneous imaging of multiple molecular targets.

Compact Design Does not require a dark room or additional infrastructure.

• Operates on a standard laboratory bench.
• Ideal for researchers needing accessible super-resolution capabilities.

Automation Features Streamlines the identification of regions of interest.

• Facilitates rapid data acquisition from thousands of synaptic proteins.
• Enhances efficiency in neuroimaging workflows.

Benefits

Enhanced Diagnostic Capabilities Supports early diagnosis and characterization of neurodegenerative diseases.

• Enables the identification of disease-linked markers.
• Facilitates the development of targeted therapies.

Accelerated Drug Development Speeds up the characterization of neurodegenerative, psychiatric, or neurodevelopmental disorders.

• Supports rapid drug profiling with minimal sample requirements.
• Enhances cost efficiency in drug development processes.