MonolixSuite is a comprehensive and powerful suite of applications specifically designed for Model Informed Drug Development (MIDD) computing. It offers a fast, intuitive, and effective platform for pharmacometrics analysis, modeling, and simulation. The suite's applications are fully interoperable, providing a complete and seamless modeling and simulation workflow. This workflow spans from initial data visualization and non-compartmental analysis (NCA) through to advanced population modeling and simulations. MonolixSuite is recognized for its advanced calculation capabilities, reliability in complex modeling scenarios, adherence to rigorous industry standards, and the ability to expedite workflows by seamlessly moving between different analysis stages, such as population PK modeling, simulation, and exposure calculation. The software aims to make pharmacometrics work more efficient, allowing users to obtain results faster by automating plotting, reducing the need for extra coding and quality control time, and streamlining the transfer of code and profiles between modules. It serves as a cornerstone toolkit for professionals in the drug development industry, supporting critical decision-making processes with high-quality, reliable data and models.

Features & Benefits

• Main Features
  • Integrated Bootstrap with results displayed directly in the Monolix results tab.
  • Plot Presets to transfer plot customization between plots and save presets for application to other projects.
  • Faster reload of projects and plots, and accelerated run times for increased efficiency.
  • Compatibility with input datasets in SAS and Excel formats for broader data integration.
  • Sparse Data option to calculate NCA parameters from mean profiles.
  • Addition of a table of concentrations, custom NCA parameters, and ratio calculations.
• Core Modules
  • MonolixSuite comprises key applications—Monolix, PKanalix, and Simulx—which together provide a complete and integrated pharmacometrics workflow.
  • Monolix: An easy, fast, and powerful tool for parameter estimation in non-linear mixed effect models, model diagnosis and assessment, and advanced graphical representation.
  • PKanalix: Supports comprehensive PK/PD analysis.
  • Simulx: Facilitates robust PK/PD simulations.
• Complete Workflow Interoperability
  • Applications are fully interoperable, enabling a seamless workflow from data visualization and non-compartmental analysis to population modeling and simulations.
• Advanced Calculation Capabilities
  • Offers intuitive, effective, and highly advanced calculation capabilities for complex pharmacometrics analysis.