Overview

Lung PD-L1 AI is an automated, AI-based decision-support tool that standardizes scoring of PD-L1 IHC in non-small cell lung cancer (NSCLC) on whole slide images (WSI) in accordance with clinical scoring guidelines. Lung PD-L1 AI is seamlessly integrated into the HALO AP® diagnostic digital pathology platform.

Intended Use

Lung PD-L1 AI is For Research Use Only and not intended for clinical diagnostic use.

Inputs

Lung resections and core biopsies

Key Outputs

Tumor Proportion Score (TPS)

Supported Clones

SP263, 22C3

File Formats

• Non-proprietary (JPG, TIF, OME. TIFF, DICOM [DCM*])
• Leica (SVS, AFI, SCN, LIF)
• Hamamatsu (NDPI, NDPIS)
• Philips (iSyntax, i2Syntax)
• 3DHistech (MRXS)
• Nikon (ND2)
• Akoya (QPTIFF, component TIFF)
• Olympus / Evident (VSI)
• Zeiss (CZI)
• Ventana (BIF) 
• KFBIO (KFB, KFBF)
• *whole slide images

Benefits

Standardize PD-L1 Evaluation

Standardization facilitates comparison across individuals, laboratories, and institutes, which in turn enables collaborative research, enhances data reliability, and ultimately advances scientific understanding.

Increase Your Workflow Efficiency

Lung PD-L1 AI can assist pathologists and researchers in conducting more efficient PD-L1 expression evaluation. The algorithm can be run on slides before they are released for review, so you can make faster and more informed decisions.

Complement Your Expertise

Lung PD-L1 AI complements your expertise and provides an easy-to-read visual mask that highlights tumor areas and positive and negative cells with colorimetric feedback. Analysis results include cell-level information, informing your PD-L1 IHC evaluation process.

Comprehensive Analysis

Lung PD-L1 AI assay reports a comprehensive set of results, including TPS score, total cell count, number of tumor cells, and number of PD-L1 positive and negative tumor cells. The Lung PD-L1 AI algorithm includes built-in and validated AI-based exclusion of artifact and benign epithelial regions with markups that can be verified by the pathologist, so you can be certain that analysis is performed accurately and consistently each and every time.

Seamless Deployment in HALO AP®

Lung PD-L1 AI is deployed and fully integrated into HALO AP®, the AI-powered, pathologist-driven platform for anatomic pathology workflows from Indica Labs.