
LentiVector PlatformOxford Biomedica
Oxford Biomedica's LentiVector™ platform is the first commercially approved lentiviral-based gene delivery system. It offers optimized processes for higher drug substance yields, superior quality, and reliable commercial manufacturing, supporting FDA-approved therapies.
Vendor
Oxford Biomedica
Company Website
OXB_Analytics_f…ctors-_2023_v11.pdf
Clinical-C…al-Vectors.pdf
LentiVecto…acturing-1.pdf
Product details
Discover our unique LentiVector™ platform
Our Services
We provide a flexible service offering designed to support you wherever you are in your development journey – whether you are in early phase or ready for commercial GMP manufacturing.
- Construct & Plasmid Design
- Analytical Method Development
- Process Development
- GMP Cell Banking
- GMP Manufacturing
- QA Release
- Stability Studies
- Regulatory Support
The LentiVector™ platform
The LentiVector™ platform is the world’s first lentiviral-based gene delivery system to be commercially approved. The platform can provide:
- Optimised processes producing higher titers of drug substance per batch than traditional processes
- Reliable commercial quality, notably supporting the first FDA approved CAR-T cell therapy
- Best-in-class perfusion bioreactor process that offers superior yield and quality
- An established serum-free suspension bioreactor process
- Automated product-specific design of experiment
- Minimal 3rd generation vector systems with key safety features
- Expertise with different lentiviral-based vectors (HIV, SIV, EIAV) and using various pseudotypes to target specific cells
- Large suite of in-house analytical methods recognised by regulatory bodies for an accelerated GMP batch release
- Access to unique chemical and mRNA enhancers to boost productivity
- 4th generation lentiviral vector system offering higher quality and potency
- Optimised cell lines for a scalable manufacturing process