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LentiVector PlatformOxford Biomedica

Oxford Biomedica's LentiVector™ platform is the first commercially approved lentiviral-based gene delivery system. It offers optimized processes for higher drug substance yields, superior quality, and reliable commercial manufacturing, supporting FDA-approved therapies.

Vendor

Vendor

Oxford Biomedica

Company Website

Company Website

OXB_Analytics_f…ctors-_2023_v11.pdf
Clinical-C…al-Vectors.pdf
LentiVecto…acturing-1.pdf
Product details

Discover our unique LentiVector™ platform

Our Services

We provide a flexible service offering designed to support you wherever you are in your development journey – whether you are in early phase or ready for commercial GMP manufacturing.

  • Construct & Plasmid Design
  • Analytical Method Development
  • Process Development
  • GMP Cell Banking
  • GMP Manufacturing
  • QA Release
  • Stability Studies
  • Regulatory Support

The LentiVector™ platform

The LentiVector™ platform is the world’s first lentiviral-based gene delivery system to be commercially approved. The platform can provide:

  • Optimised processes producing higher titers of drug substance per batch than traditional processes
  • Reliable commercial quality, notably supporting the first FDA approved CAR-T cell therapy
  • Best-in-class perfusion bioreactor process that offers superior yield and quality
  • An established serum-free suspension bioreactor process
  • Automated product-specific design of experiment
  • Minimal 3rd generation vector systems with key safety features
  • Expertise with different lentiviral-based vectors (HIV, SIV, EIAV) and using various pseudotypes to target specific cells
  • Large suite of in-house analytical methods recognised by regulatory bodies for an accelerated GMP batch release
  • Access to unique chemical and mRNA enhancers to boost productivity
  • 4th generation lentiviral vector system offering higher quality and potency
  • Optimised cell lines for a scalable manufacturing process
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