Advancing Discovery with Trainable AI

Insightful and robust AI creation for pathology

Unlock Limitless Possibilities with HALO AI

HALO AI has you covered. Whether you’re looking to solve image analysis challenges in segmentation, classification, or phenotyping, the advanced deep learning networks of HALO AI are easily tuned for your specific application with the train-by-example interface.

Diverse and Powerful AI

Underpinned by modern deep learning networks, HALO AI provides a collection of segmentation, classification, and phenotyping tools for brightfield and fluorescence applications. Train a classifier to quantify tissue classes, to find rare events or cells in tissues, or to categorize cell populations into specific phenotypes.

AI-Powered Annotation

Use a point and click workflow to rapidly annotate images and develop training data.

Nuclear Segmentation

Choose between several trainable AI-based nuclear segmentation networks to optimize segmentation accuracy when nuclear morphologies vary.

Membrane Segmentation

Train AI-powered membrane segmentation networks to accurately delineate cell membranes for your specific assay.

Tissue Segmentation

Train AI-based MiniNet and DenseNet networks to classify tissue into user-defined classes.

Cell & Object Phenotyping

Quickly train a phenotyper to quantify cell types or objects of interest.

Slide Quality Control

Leverage a trainable AI-powered quality control network to detect common artifacts in H&E and IHC images.

Simple & Intuitive Workflow

HALO AI is fully integrated with the intuitive, easy-to-use HALO® and HALO Link platforms and employs a simple three-step workflow. After defining tissue classes or cell phenotypes, you train the neural network by drawing annotations – no computer programming or AI knowledge required. 

• Define Classes
• Train Network
• Apply Classifier

Manage Variability

Extreme variability runs rife in image analysis but is no match for HALO AI. Common sources of variability include diverse morphologies, alterations of morphologies from staining protocols, differences in tissue quality, uneven staining, and more. HALO AI can be easily trained to accommodate variability to deliver accurate segmentation and classification results across large studies. HALO AI can even be trained to work across vastly different stains such as PAMS, Trichrome, H&E, and IHC.

Exceptional Identification

Pre-trained nuclear and membrane segmentors available in HALO are advanced tools for nuclear and membrane segmentation, but when you need to optimize a network for a bespoke application, you need HALO AI. As with the tissue classification and segmentation networks, you can quickly add training data with the AI-based annotation tool and train the network to optimally segment nuclei or cell membranes. And once trained, any HALO AI network can be incorporated into HALO modules for maximum utility.

Powerful Tissue Classification

The degree of variability encountered in pathology often demands an approach above and beyond a simple random forest tissue classifier. HALO AI has two advanced pre-trained networks capable of creating high-resolution classifiers in brightfield and fluorescence, depending on how much training data and time are available for training and optimization.

Advanced Phenotyping

Cell phenotyping can be used on any of the myriad supported image types to automatically assign cells into user defined phenotypes. Simply select a nuclear or membrane segmentation network, provide a few quick training examples, and train the network to identify phenotypes of interest. Phenotyping is a highly effective and flexible tool to quantify cells based on morphology when biomarker information is absent and can assist with quantification and characterization of cells with complex morphologies, such as neuronal cells.

Top Notch Training and Support

At Indica Labs, we take pride in providing top-quality support. Unlimited IT support, scientific support, training, and access to our Learning Portal are included with every license at no additional cost. With support staff in the US, UK, EU, China, and Japan, you are supported in any time zone.